No, not really. The Sony WH-1000XM6 isn't built for exercise, and Sony explicitly says so. There's no water or sweat resistance, and moisture damage isn't covered under warranty.
Why they don't work for workouts:
These are luxury over-ear headphones designed for flights, offices, and home listening. They're engineered for comfort in controlled environments, not bouncing around during a workout.
Running? The headphones shift constantly. HIIT or anything involving jumping? Forget it.
Even during light exercise, the closed-back design traps heat. After 20 minutes, your ears will be warm and sweaty. That moisture can damage the drivers and break down ear cushions over time.
If you really want to try:
For low-impact activities like treadmill walking or stationary bikes, some people make it work.
Third-party sweat covers from companies like Wicked Cushions create a silicone barrier between your sweat and the headphones. Not perfect, but better than nothing.
What you should actually use:
For the gym, get earbuds designed for exercise. Sony's WF-1000XM5 earbuds have IPX4 sweat resistance. Beats Fit Pro and AirPods Pro 2 are other solid options.
The XM6 is excellent at almost everything, but exercise isn't one of them.
Compare Sony WH-1000XM6 prices to find the best deal.