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Medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Minimizer, Dead Skin Cells Improvement | Korean Skin Care 1.01 fl.oz

TLDR Review: Medicube Zero Exosome Shot Serum

Item: Medicube Zero Exosome Shot Serum
Author: ShopSavvy

By ShopSavvy Team

Published: January 30th, 2026

Pros

•Delivers noticeably soft and smooth skin texture after just one application
•Absorbs quickly in about a minute without leaving sticky residue
•Particularly effective at deep cleaning and visibly minimizing pores
•Produces results comparable to professional microneedling treatments
•Extremely affordable pricing for the quality and results achieved
•Increases blood flow and creates visible plumping effect that shrinks pores
•Produces noticeable glow and radiance the morning after application
•Works synergistically with hydrating serums and collagen products to enhance penetration
•High potency formula (2000 PPM) delivers visible antging results including visible fading of forehead lines
•Noticeable results within 3 weeks with continued use

Cons

•High potency formula (2000 PPM) is not suitable for beginners and causes immediate irritation
•Creates intense prickling sensation when massaged in that can feel like brief hives
•Produces mild redness that fades within days
•Prickling sensation can be ofutting, especially on first use despite being manageable
•Intensity of sensation depends on how long you leave it on before applying moisturizer

Bottom Line

This is a legitimate at-home alternative to professional microneedling that delivers genuinely impressive results—including visible pore minimization and anti-aging benefits—at a fraction of the cost. The intense prickling sensation is real and not for the faint of heart, but reviewers consistently agree it's worth pushing through since results show up quickly (within 3 weeks) and the discomfort becomes tolerable with use. If you have sensitive skin or are new to active ingredients, start slowly and apply a hydrating moisturizer within 10 minutes to dial down the intensity while keeping the benefits intact.